abstract：:The aims of this study were to quantify the prevalence of pain among hospitalized Italian patients and to describe the potential determinants of pain in this population. All patients older than 18 years and hospitalized for at least 24 hours in one of the 30 public hospitals of the Liguria region (n = 4709) were eligi...

journal_title：Journal of pain and symptom management

authors： Costantini M,Viterbori P,Flego G

更新日期：2002-03-01 00:00:00

abstract：:Delirium often causes severe distress for terminally ill cancer patients, and treatment of underlying pathologies is important to achieve symptom alleviation. Although accumulation of morphine metabolites may play an important role in development of delirium, empirical findings are conflicting due to a large inter-ind...

journal_title：Journal of pain and symptom management

authors： Morita T,Tei Y,Tsunoda J,Inoue S,Chihara S

更新日期：2002-02-01 00:00:00

abstract：:The technology of telemedicine has been used for over 20 years, involving different areas of medicine, providing medical care for the geographically isolated patients, and uniting geographically isolated clinicians. Today audio-visual technology may be useful in palliative care for the patients lacking access to medic...

journal_title：Journal of pain and symptom management

authors： Coyle N,Khojainova N,Francavilla JM,Gonzales GR

更新日期：2002-02-01 00:00:00

abstract：:To evaluate the role of oral ketamine as an adjuvant to oral morphine in cancer patients experiencing neuropathic pain, 9 cancer patients (5 men, 4 women) taking maximally tolerated doses of either morphine, amitriptyline, sodium valproate, or a combination of these drugs for intractable neuropathic pain, and reportin...

journal_title：Journal of pain and symptom management

authors： Kannan TR,Saxena A,Bhatnagar S,Barry A

更新日期：2002-01-01 00:00:00

abstract：:To assess the psychometric properties of the Hot Flash Related Daily Interference Scale (HFRDIS), a sample of breast cancer survivors and an age-matched comparison group completed a questionnaire packet and 2-day prospective hot flash diary at an initial time point and again 6 months later. There were 71 breast cancer...

journal_title：Journal of pain and symptom management

authors： Carpenter JS

更新日期：2001-12-01 00:00:00

abstract：:The purpose of this study was to evaluate the technical possibilities of placing a catheter near the celiac plexus for performance of a celiac plexus block, and to study the efficacy of repeated neurolytic celiac plexus blocks with alcohol in patients with advanced pancreatic cancer pain resistant to opioid treatment....

journal_title：Journal of pain and symptom management

authors： Vranken JH,Zuurmond WW,de Lange JJ

更新日期：2001-11-01 00:00:00

abstract：:The results of a novel approach to the use of ketamine in refractory cancer pain are reported. In this prospective, multicenter, unblinded, open-label audit, 39 patients (with a total of 43 pains) received a short duration (3 to 5 days) ketamine infusion. The initial dose of 100 mg/24 hr was escalated if required to 3...

journal_title：Journal of pain and symptom management

authors： Jackson K,Ashby M,Martin P,Pisasale M,Brumley D,Hayes B

更新日期：2001-10-01 00:00:00

abstract：:Assessing quality of care at the end of life involves measurements in several domains-use of evidence-based guidelines, patient and family satisfaction, quality of life, and incidence of adverse events, among others. There are several different data sources from which to calculate quality measures. Each data source ha...

journal_title：Journal of pain and symptom management

authors： Nerenz DR

更新日期：2001-09-01 00:00:00

abstract：:The increasing number of palliative care patients necessitates a simple, reliable instrument to routinely measure outcomes among hospice patients. We tested the utility of the Brief Hospice Inventory (BHI) to assess outcomes of hospice patients and estimations of patients' outcomes by nurse caregivers. In a prospectiv...

journal_title：Journal of pain and symptom management

authors： Guo H,Fine PG,Mendoza TR,Cleeland CS

更新日期：2001-08-01 00:00:00

abstract：:Although pain is an extremely common symptom presenting to primary care physicians, it frequently is not optimally managed. The purpose of this feasibility study was to develop and pilot-test an efficient, rapid assessment and management approach for pain in busy community practices. The intervention utilized the Dart...

journal_title：Journal of pain and symptom management

authors： Ahles TA,Seville J,Wasson J,Johnson D,Callahan E,Stukel TA

更新日期：2001-07-01 00:00:00

abstract：:A blinded meta analysis was performed on randomized clinical trials (RCT) on the medicinal treatment of reflex sympathetic dystrophy (complex regional pain syndrome type I) to assess the methodological quality and quantify the analgesic effect of treatments by calculating individual and summary effect sizes. The inter...

journal_title：Journal of pain and symptom management

authors： Perez RS,Kwakkel G,Zuurmond WW,de Lange JJ

更新日期：2001-06-01 00:00:00

abstract：:Patients with chronic pain often complain of difficulties with cognitive functioning. Previous studies suggest that these occur with no history of head trauma or neurological disease. This study examined potential predictors of cognitive complaints in 275 consecutive patients referred to a university pain management c...

journal_title：Journal of pain and symptom management

authors： McCracken LM,Iverson GL

更新日期：2001-05-01 00:00:00

abstract：:Variations in treatment effects between drug trials are usually attributed to different patient characteristics, variations in outcome assessment, and random error. We have previously hypothesized that part of the variation in treatment effects between drug trials might be caused by differences in nonspecific factors....

journal_title：Journal of pain and symptom management

authors： de Craen AJ,Lampe-Schoenmaeckers AJ,Kraal JW,Tijssen JG,Kleijnen J

更新日期：2001-03-01 00:00:00

abstract：:The hospice model of care of the dying patient is regarded as a model of excellence; however, outcomes of this care have been poorly demonstrated. Integrated Care Pathways (ICPs) provide a method of recording and measuring outcomes of care. The ICP document replaces all previous documentation and is a multiprofessiona...

journal_title：Journal of pain and symptom management

authors： Ellershaw J,Smith C,Overill S,Walker SE,Aldridge J

更新日期：2001-01-01 00:00:00

abstract：:A retrospective analysis was performed to describe the course of terminal care provided to dying hospitalized children in terms of symptom assessment and management, and communication and decision-making, at the end of life. Seventy-seven of 236 infants and children who died after hospital admission in Edmonton, Canad...

journal_title：Journal of pain and symptom management

authors： McCallum DE,Byrne P,Bruera E

更新日期：2000-12-01 00:00:00

abstract：:Two young women with chronic nausea and vertigo caused by multiple sclerosis responded to the introduction and maintenance of the 5HT3 receptor antagonist, ondansetron. Palliative care is a neglected aspect of management of degenerative neurological diseases and these cases highlight the approaches that may be used to...

journal_title：Journal of pain and symptom management

authors： Macleod AD

更新日期：2000-11-01 00:00:00

abstract：:The objective of this study was to compare the efficacy and tolerability of gabapentin and amitriptyline monotherapy in painful diabetic neuropathy. This was a 12-week, open-label, prospective, randomized trial. Twenty-five type-II diabetic patients with pain attributed to diabetic neuropathy and a minimum score of 2 ...

journal_title：Journal of pain and symptom management

authors： Dallocchio C,Buffa C,Mazzarello P,Chiroli S

更新日期：2000-10-01 00:00:00

abstract：:Cytokines have a major role in promoting the growth and spread of cancers. Elevated levels of several cytokines have been described in cancer patients. Evidence from animal and human studies suggests that cytokines may contribute to a wide range of symptoms in advanced cancer, including: asthenia, pain, drowsiness, co...

journal_title：Journal of pain and symptom management

authors： Dunlop RJ,Campbell CW

更新日期：2000-09-01 00:00:00

abstract：:The psychometric characteristics of the Faces Pain Scale (FPS) were evaluated in three groups of preschool and school-aged children (3. 5-4.5; 4.5-5.5 and 5.5-6.5 years, respectively). The FPS was adequately comprehended by even young children. It was easily administered and was valid and discriminating. It did not, h...

journal_title：Journal of pain and symptom management

authors： Hunter M,McDowell L,Hennessy R,Cassey J

更新日期：2000-08-01 00:00:00

abstract：:This study examined the differences in the prescription and administration of analgesics in eight pediatric specialty units. Medical records of patients (n = 153) who were reported by nurses to be having pain were reviewed. Results showed that there were variations in the type of analgesics prescribed and administered...

journal_title：Journal of pain and symptom management

authors： Jacob E,Puntillo KA

更新日期：2000-07-01 00:00:00

abstract：:Many patients suffer from chronic, intractable neuropathic pain. Despite similar diagnoses and presumed pathophysiologies, symptoms and response to treatment can differ. Monotherapy is only occasionally successful. In this prospective survey, 20 patients with chronic, neuropathic pain not responding to interventional ...

journal_title：Journal of pain and symptom management

authors： Devulder J,De Laat M

更新日期：2000-05-01 00:00:00

abstract：:Advanced dementia patients may be at substantial risk for undetected or undertreated pain. To examine the treatment of pain following hip fracture, a prospective cohort study was conducted in an academic teaching hospital. Fifty-nine cognitively intact elderly patients with hip fracture and 38 patients with hip fractu...

journal_title：Journal of pain and symptom management

authors： Morrison RS,Siu AL

更新日期：2000-04-01 00:00:00

abstract：:The effectiveness of docusate for constipation has not been studied in the terminally ill. Controversy also exists concerning its effectiveness in the chronically ill. Because chronically ill patients and terminally ill patients have several risk factors for constipation in common, we undertook a systematic review of ...

journal_title：Journal of pain and symptom management

authors： Hurdon V,Viola R,Schroder C

更新日期：2000-02-01 00:00:00

abstract：:More than 2200 subjects were enrolled in the MorphiDex (MS:DM) development program, with a 1:1 (weight:weight) ratio of morphine sulfate (MS) to dextromethorphan hydrobromide (DM). Of the 1400 subjects exposed to MorphiDex, more than 350 subjects were treated for at least 6 months, and over 200 subjects were treated f...

journal_title：Journal of pain and symptom management

authors： Goldblum R

更新日期：2000-01-01 00:00:00

abstract：:Visual analogue scales (VAS) and verbal rating scales (VRS) are widely used to assess pain. This paper presents a secondary analysis of a subsection of data collected as part of an evaluation of an intervention to improve nighttime pain. The aims were to describe the relationship between the VAS and VRS; to compare ch...

journal_title：Journal of pain and symptom management

authors： Briggs M,Closs JS

更新日期：1999-12-01 00:00:00

abstract：:As many as 90% of patients with cancer-related pain can attain satisfactory relief through available pharmacological and medical means. However, as many as 45% of patients in the earlier stages of cancer and 75% of patients in the advanced stages experience at least some pain. Although published guidelines are availab...

journal_title：Journal of pain and symptom management

authors： Pargeon KL,Hailey BJ

更新日期：1999-11-01 00:00:00

abstract：:Although sialorrhea and drooling are uncommon symptoms in cancer patients, they can cause considerable discomfort, inconvenience and social embarrassment. In this article we describe a patient with tongue cancer who was successfully treated with oral glycopyrrolate 0.4 mg 3 times daily. Glycopyrrolate is a quaternary ...

journal_title：Journal of pain and symptom management

authors： Olsen AK,Sjøgren P

更新日期：1999-10-01 00:00:00

abstract：:Concerns about the safety of therapy with methadone, which may arise because of its pharmacokinetic characteristics and inappropriate dosing, may deter clinicians from using this drug, especially in elderly patients. Experience is accumulating that the drug may be used safely and successfully if low doses are given in...

journal_title：Journal of pain and symptom management

authors： Mercadante S,Casuccio A,Agnello A,Barresi L

更新日期：1999-09-01 00:00:00

abstract：:The use of cardiac pacemakers and arrhythmia control devices is increasingly common. The presence of a previously placed pacemaker or implantable cardioverter-defibrillator (ICD) in a terminally ill patient may result in medical and ethical issues for the patient, family, and healthcare provider. Two cases are present...

journal_title：Journal of pain and symptom management

authors： Braun TC,Hagen NA,Hatfield RE,Wyse DG

更新日期：1999-08-01 00:00:00

abstract：:Although the "opioid contract" is widely used in the administration of chronic opioid therapy, its use has not been well defined and there are few guidelines for developing or revising such tools. We reviewed opioid contracts from 39 major academic pain centers and analyzed every statement for its core meaning. These ...

journal_title：Journal of pain and symptom management

authors： Fishman SM,Bandman TB,Edwards A,Borsook D

更新日期：1999-07-01 00:00:00

abstract：:Gabapentin was administered as an "add on" therapy to 22 patients with neuropathic cancer pain only partially responsive to opioid therapy. Global pain, burning pain, shooting pain episodes, and allodynia were assessed separately. Gabapentin was given for at least a week and efficacy was assessed after 7 to 14 days of...

journal_title：Journal of pain and symptom management

authors： Caraceni A,Zecca E,Martini C,De Conno F

更新日期：1999-06-01 00:00:00

abstract：:As more individuals are being treated for cancer with high-dose therapy and autologous stem cell rescue (ASCR), there is growing interest in treatment side effects and their impact on quality of life. The primary aim of this study was to determine if the severity of fatigue and its impact on quality of life is signifi...

journal_title：Journal of pain and symptom management

authors： Hann DM,Garovoy N,Finkelstein B,Jacobsen PB,Azzarello LM,Fields KK

更新日期：1999-05-01 00:00:00

abstract：:The United States Agency for Health Care Policy and Research (AHCPR) Acute Pain Management Guidelines were written to provide a scientific basis for practice. Educational programs designed to promote use of the guidelines may change practice in community hospitals. This article describes the development and implementa...

journal_title：Journal of pain and symptom management

authors： Dalton JA,Blau W,Lindley C,Carlson J,Youngblood R,Greer SM

更新日期：1999-04-01 00:00:00

abstract：:The effect of iontophoretic administration of vincristine in the treatment of postherpetic neuralgia (PHN) was investigated in a prospective, double-blind, placebo-controlled trial. Twenty patients with intercostal or lumbar PHN for more than 6 months that was unresponsive to conventional medical therapy were randomiz...

journal_title：Journal of pain and symptom management

authors： Dowd NP,Day F,Timon D,Cunningham AJ,Brown L

更新日期：1999-03-01 00:00:00

abstract：:A mathematical rate is composed of a numerator, denominator, and time period of observation. Deciding who is in the denominator is a key, yet difficult task given the blurred boundaries of chronic illness, in examining the quality of care for dying patients. We propose two potential solutions. First, one could prospec...

journal_title：Journal of pain and symptom management

authors： Teno JM,Coppola KM

更新日期：1999-02-01 00:00:00

abstract：:Assessing for the presence of addiction in the chronic pain patient receiving chronic opioid analgesia is a challenging clinical task. This paper presents a recently developed screening tool for addictive disease in chronic pain patients, and pilot efficacy data describing its ability to do so. In a small sample of pa...

journal_title：Journal of pain and symptom management

authors： Compton P,Darakjian J,Miotto K

更新日期：1998-12-01 00:00:00

abstract：:Recent research has shown that the psychostimulant drug dextroamphetamine can increase the analgesia produced by opioids. Despite the strong, positive results in human clinical subjects and in animals, this combination is rarely used in clinical practice. The purpose of this paper is to investigate whether the psychos...

journal_title：Journal of pain and symptom management

authors： Dalal S,Melzack R

更新日期：1998-10-01 00:00:00

abstract：:This study sought to characterize the nature of breakthrough pain experienced by 22 hospice patients and to assess the perceptions of their respective caregivers. Questionnaires were administered by trained hospice nurses to determine key elements of episodic pains in this home-based terminally ill population. Eighty-...

journal_title：Journal of pain and symptom management

authors： Fine PG,Busch MA

更新日期：1998-09-01 00:00:00

abstract：:The purpose of this study was to determine physicians' attitudes toward and preferences for palliative management of malignant ascites. A random sample of eighty physicians practicing in Canada was selected from the memberships of the Canadian Association of Medical Oncologists, the Canadian Association of Gastroenter...

journal_title：Journal of pain and symptom management

authors： Lee CW,Bociek G,Faught W

更新日期：1998-08-01 00:00:00

abstract：:Rational drug treatment of chronic musculoskeletal pain remains a challenge. Although commonly prescribed, the true efficacy of opioid analgesics or of nonsteroidal antiinflammatory drugs remains to be established. Using an N-of 1 design, eight patients with regional cervicobrachial pain received ibuprofen 800 mg/day,...

journal_title：Journal of pain and symptom management

authors： Sheather-Reid RB,Cohen M

更新日期：1998-04-01 00:00:00